PHARMACY (MEDICINE )

                                        Top 10 benefits to using turmeric for your Health 1-It contains bioactive compounds with very powerful medicinal purposes,   it contains something called curcumin which is the antimicrobial,  anti-inflammatory, and antioxidant substance that makes up most of the turmeric.   2- Turmeric is a natural anti-inflammatory curcumin which is in Turmeric has been shown to have natural anti-inflammatory properties so in  particular this has been shown to play a major role in reducing inflammation throughout the body.   3- Turmeric has been shown to increase antioxidant properties within the body this is important to get rid of free radicals inside your body and to release all toxins at your body that might be accruing over time.   4- Curcumin has been linked to improving brain function this is important for people who s...

  H2 RECEPTOR ANTAGONIST TOXICITY, SPECIFIC INGESTION & TREATMENT:                                                                  H2 RECEPTOR ANTAGONIST: Intro of Drugs: ·        Reduce acids which are produced by the Lining of the Stomach ·        Include cimetidine, famotidine, nizatidine, ranitidine Available dosage forms : ·        Oral Route, IV route   Toxicokinetics: ·        Therapeutic Bioavailability Cimetidine:60-70% ·        Therapeutic Bioavailability famotidine : 40-45% ·    ...

  THEOPHYLLINE   TOXICITY, SPECIFIC   INGESTION & TREATMENT : THEOPHYLLINE : Intro of   Drug :         Theophylline occurs in tea and cocoa beans in trace amounts. Available dosage forms :    Liquid sustained-release tabs, caps & parenteral.   Toxicokinetics: ·         Well absorbed Orally  Volume of distribution approx. 0.5L/Kg ·         Hepatically metabolized ·         Clearance depends on age, disease states & interacting drugs. Clinical Presentation: ·        a feeling of loathing   ·         Vomit ·      Convulsion ·         Cardiac Dysrhythmias ·         Chronic toxicity  Laboratory Data: A-      Theophyll...

  PARACETAMOL (ACETAMINOPHEN) TOXICITY , SPECIFIC  INGESTION & TREATMENT :                                          Acetaminophen  (Paracetamol) : Def: ·         an antipyretic –analgesic ·         can produce fatal Hepatotoxicity in the untreated patient through toxic metabolite Available dosage forms : ·         Available in a variety of OTC & Prescription drug products. Toxicokinetics: ·         Well  absorbed from GIT ·         Half-life between 2 and 3 hrs. ·         Less than 5% excreted in Urine ·         Remainder metabolized in the liver by Cytochrome P450 Clinical Presentation: 1- Phase I (12 to 24Hrs Po...

  Coffee and associated health benefits: What is Coffee: Coffee is actually derived from the coffee bean which is a seed of the raffia plant so it's a very popular beverage utilized around the world. Composition: coffee contains over 1 000 bioactive compounds including caffeine antioxidants and another group of compounds known as dieter paranoids. Action: Caffeine can actually cross the blood-brain barrier enter the brain and have effects on neurons in our brain so here is a neuron here so caffeine binds to adenosine receptors so it actually binds to several adenosine receptors a1 a2a a2b and a3 a2a it's binding to a2a is actually what mediates its stimulant effects and this leads to the release of excitatory neurotransmitters and this is going to become important when we talk about certain health effects later on so again caffeine can cross the blood-brain barrier enter the brain and bind to adenosine receptors and particularly h2a is what we see with its s...

  How to get rid of a headache Naturally: how to get rid of a headache in five minutes without pills when you have a headache and the pill you need isn't at hand the situation seems hopeless but it isn't so there's a scientific way to get rid of a headache called acupressure, this technique which removes a headache effectively and quickly. Acupressure is a kind of massage the effectiveness of which is confirmed by numerous scientific studies by its nature it's a form of acupuncture and reflex therapy but it doesn't require special medical knowledge do know how to massage acupressure points first take a comfortable position and relax completely the massage doesn't take much time from 30 seconds to 1 minute on average there are six main points to get rid of a headache easily and quickly massage a point with a light press or circular movements usually the headache disappears during the massage or five to ten minutes after it the first one is Yin Tang point th...

  PARAECETAMOL SIDE EFFECTS :         headache         fever         body pains that one medicine that comes to your mind is paracetamol but remember there are side effects of taking paracetamol yes that's correct Paracetamol is usually prescribed in cases of mild to moderate pain and in cases where people tend to develop pain after delivery fevers and also in pregnancy statuses it is also given as a painkiller in conditions where people are allergic to the drug called aspirin bronchial asthma peptic ulcers so now what is the recommended dosage of Paracetamol it varies uh based upon your body weight but the most commonly considered uh dosage is 500 mm given three times a day it again varies depending upon the body type and that particular decision is taken by the treating doctor alone. Side Effects AS Therapeutic Dose: side effects of taking paracetamol even in the therapeutic dosages paracetamol can cause ra...

  PARACETAMOL TOXICITY : Metabolism: the metabolism of acetaminophen, identify the key toxic metabolite, describe the clinical presentation of acetaminophen toxicity, and discuss the treatment and antidote for acetaminophen toxicity. We will start with a general discussion about acetaminophen and then talk about its pharmacology and metabolism and how this applies to acetaminophen toxicity. We'll then discuss the clinical presentation and finally the treatment for acetaminophen toxicity. About Paracetamol: Acetaminophen is one of the most commonly used analgesics in antipyretics today. It is in many over-the-counter medications as well as in many prescription medications in combination with various opioids. Because of this, in addition to acetaminophen toxicity, you must consider toxicity from other medications in acute and chronic ingestions. Many consider acetaminophen to be a benign medication. However, it is the most common cause of acute fulminate liver failure...