Coffee and associated health benefits :

 

Coffee and associated health benefits:

What is Coffee:

Coffee is actually derived from the coffee bean which is a seed of the raffia plant so it's a very popular beverage utilized around the world.

Composition:

coffee contains over 1 000 bioactive compounds including caffeine antioxidants and another group of compounds known as dieter paranoids.

Action:

Caffeine can actually cross the blood-brain barrier enter the brain and have effects on neurons in our brain so here is a neuron here so caffeine

binds to adenosine receptors so it actually binds to several adenosine receptors a1 a2a a2b and a3 a2a it's binding to a2a is actually what mediates its stimulant effects and this leads to the release of excitatory neurotransmitters and this is going to become important when we talk about certain health effects later on so again caffeine can cross the blood-brain barrier enter the brain and bind to adenosine receptors and particularly h2a is what we see with its stimulatory effects and it oftentimes leads to increased excitatory neurotransmitters so we're going to first talk about neurological health benefits that are associated with coffee.

Coffee Consumption and Disease Prevention:

 coffee consumption may reduce the risk of some neurological diseases including Parkinson's disease as was found in this article entitled meta-analysis of coffee drinking cigarette smoking and the risk of Parkinson's disease and there may be a small reduction in the risk of Alzheimer's disease with coffee consumption as well one mouse model actually demonstrated reduced beta-amyloid so beta-amyloid is important in the pathogenesis or pathophysiology of Alzheimer's disease and these two articles both show some reduction in risk of Alzheimer's disease with coffee consumption or an associated reduction in risk so the two articles here are entitled caffeine protects Alzheimer's mice against cognitive impairment and reduces brain beta-amyloid production so this was mentioned here and then the other article is Alzheimer's disease and coffee a quantitative review.

Decaffeinated Coffee:

decaffeinated coffee also showed similar findings so an individual increases their consumption of decaffeinated coffee their risk of all-cause mortality decreases as well now coffee consumption is also associated with decreased incidence of and all-cause mortality from the following cardiovascular disease coronary heart disease and cerebrovascular disease and from a lot of the studies that were mentioned in this article.

Intake of Coffee:

It seemed that three cups of coffee per day was probably the best dosing with smaller decreases and smaller associated benefits with increasing doses of coffee now it was also interesting that women had slightly higher associated benefits and there was also demonstrated associated benefits after a heart attack as well so even if an individual did have coronary heart disease and they had a heart attack or myocardial infarction having coffee or consuming three cups of coffee per day after their heart attack it seemed to also have some associated benefits as well so again very interesting very important high coffee consumption seems to reduce or is associated with a reduced risk of all-cause mortality and is also associated with a decreased incidence of all-cause mortality from cardiovascular disease coronary heart disease and cerebrovascular disease so things like strokes now we're going to talk about cancer.