TIPS TO MANAGE MENTAL HEALTH
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FOOD DETRIMENTAL FOR BRAIN
The following list of foods is detrimental to your brain The most vital organ system in the body, the brain, requires top-notch nourishment. Some meals can hurt the brain, altering things like mood and memory. Eliminating some foods from the diet can improve brain function and protect against diseases like dementia. The following are the six worst foods for the brain, per Health line: 1. Sugary beverages Soft drinks like soda, energy drinks, and even fruit juice substitutes can raise your risk of heart disease and type 2 diabetes. These in turn leave open the possibility of dementia and Alzheimer's disease. High fructose intake causes the brain to be insulin resistant, which impairs cognition, memory, and learning. Refined carbohydrates White flour and oth...
HPLC CALIBRATION SOP
HPLC CALIBRATION SOP PURPOSE: All instruments should be calibrated and the appropriate correction applied to the original measurements. This calibration system should bring about trust in decisions or measures. 1.1 To check the performance of the instrument. 1.2 To avoid the variation/wrong result 1.3 To achieve the result according to the specification. 2.0 PROCEDURE: VALIDATION: Validation of an analytical method is a process by which it is established, by laboratory studies, that the performance characteristics of the method meet the requirements for the intended analytical applications. ANALYTICAL PERFORMANCE CHARACTERISTI...
Dexlansoprazole
M edical use Dexlansoprazole is used to maintain healing and healing of erosive esophagitis and to treat heartburn associated with gastroesophageal reflux disease (GERD). [1] It lasts longer and requires less intake than its chemically related lansoprazole. [7] There is no good evidence that it works better than other PPIs. [3] Side effects The most important adverse events (≥2%) reported in clinical trials were diarrhea, abdominal pain, bloating, nausea, upper respiratory tract infection, vomiting and flatulence. [one] movement mechanism Like lansoprazole, dexlansoprazole permanently binds to the proton pump and blocks it, preventing the formation of stomach acid. [7]
PARACETAMOL EFFECTS
Paracetamol-containing drugs, which are prescribed by specialist doctors, are used to eliminate the symptoms that occur due to flu infections. Drugs with paracetamol as an active ingredient are preferred because of their antipyretic and analgesic properties, they are colorless and bitter. Paracetamol, which is an odorless, white and crystalline powder, has a bitter taste and is soluble in water to a limited extent. When paracetamol is taken orally, it is rapidly absorbed in the gastrointestinal tract, that is, the part from the mouth to the anus where the body's chewing, digestion, absorption and excretion processes occur. Paracetamol-containing drugs reach maximum plasmas only 30 to 60 minutes after ingestion and are rapidly distributed to all tissues. The binding of drugs containing paracetamol to plasma proteins is weak.
Beta blockers
Beta blockers Beta blockers, which were first used in 1960, are drugs that reduce the workload of the heart by blocking certain effects of the sympathetic nervous system (the system responsible for events in our body during stress!) that can cause a rapid heartbeat. They are called "beta-blockers" because they block areas in the heart called "beta receptors". These beta receptors are normally activated by certain hormones (such as adrenaline) that are released during stress. When activated by stress hormones, beta receptors trigger a reaction that increases heart rate and heart rate. Beta blockers, on the other hand, prevent stress hormones from triggering this reaction by binding to beta receptors. Thus, beta-blockers reduce cardiac stress by slowing the h...
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TOP 10 BENEFITS TO USING TURMERIC FOR YOUR HEALTH
Top 10 benefits to using turmeric for your Health 1-It contains bioactive compounds with very powerful medicinal purposes, it contains something called curcumin which is the antimicrobial, anti-inflammatory, and antioxidant substance that makes up most of the turmeric. 2- Turmeric is a natural anti-inflammatory curcumin which is in Turmeric has been shown to have natural anti-inflammatory properties so in particular this has been shown to play a major role in reducing inflammation throughout the body. 3- Turmeric has been shown to increase antioxidant properties within the body this is important to get rid of free radicals inside your body and to release all toxins at your body that might be accruing over time. 4- Curcumin has been linked to improving brain function this is important for people who s...
PARACETAMOL (ACETAMINOPHEN) TOXICITY , SPECIFIC INGESTION & TREATMENT :
PARACETAMOL (ACETAMINOPHEN) TOXICITY , SPECIFIC INGESTION & TREATMENT : Acetaminophen (Paracetamol) : Def: · an antipyretic –analgesic · can produce fatal Hepatotoxicity in the untreated patient through toxic metabolite Available dosage forms : · Available in a variety of OTC & Prescription drug products. Toxicokinetics: · Well absorbed from GIT · Half-life between 2 and 3 hrs. · Less than 5% excreted in Urine · Remainder metabolized in the liver by Cytochrome P450 Clinical Presentation: 1- Phase I (12 to 24Hrs Po...
01-SOP FOR IN PROCESS CHECKS DURING MANUFACTURING AND PACKING (PHARMACEUTICAL)
SOP FOR IN PROCESS CHECKS DURING MANUFACTURING AND PACKING 1. RESPONSIBILITY AND AUTHORITY: Quality Assurance manager Q uality assurance Officer Packing Pharmacist 4. PROCEDURE: To carry out effective in-process checking control ensures that the following practices are observed by all the packing / in-process control Pharmacist. · The correct uniform, coats and head-dress must be worn at all times. Gloves and mask also be worn whenever a product is being filled into its primary package and is therefore in danger of contamination during packing. · In-process check should be carried out on every packing line after every 30minutes...
TIPS TO MANAGE MENTAL HEALTH
03- IN-PROCESS CHECKS OF TABLETS AT COMPRESSION STAGE (PHARMACEUTICAL)
03- IN-PROCESS CHECKS OF TABLET COMPRESSION · Check the status of the Q.C.'s released label and Report of Bulk in the batch production record file. · Check that the ingredients, containers, labels, and documents from preceding batches have been taken out. · Check the cleanliness of the ceiling, floor, doors, windows, and other surfaces. · Check the dust collector is turned on and operating correctly. · Check the HVAC system's functionality. · Check that the analytical balance, compression machine, and other tools are correctly cleaned and calibrated. · Check that everyone using protective gear is carrying it out correctly. · Check the physical characteristics...
QUALITY MANAGEMENT IN THE DRUG INDUSTRY
QUALITY MANAGEMENT IN THE DRUG INDUSTRY Quality management is typically referred to in the larger pharmaceutical industry as the part of the management function that chooses and puts into practice the "quality policy," or the overall intention and course of an organization about quality, as formally expressed and authorized by top management. The fundamental components of quality management are: 1— an appropriate infrastructure, or "quality system ," encompassing organizational structure, procedures, processes, and resources; 2— systematic actions required to ensure sufficient confidence that a Product ( or service) will meet predetermined standards for quality. Quality assurance refers to the sum of these efforts. The management tool of quality assurance is used within a company. Quality control also helps to build supplier confidence in contractual contexts. Aspects of quality management that are interrelated include the ideas of quality assurance, G...
HPLC CALIBRATION SOP
HPLC CALIBRATION SOP PURPOSE: All instruments should be calibrated and the appropriate correction applied to the original measurements. This calibration system should bring about trust in decisions or measures. 1.1 To check the performance of the instrument. 1.2 To avoid the variation/wrong result 1.3 To achieve the result according to the specification. 2.0 PROCEDURE: VALIDATION: Validation of an analytical method is a process by which it is established, by laboratory studies, that the performance characteristics of the method meet the requirements for the intended analytical applications. ANALYTICAL PERFORMANCE CHARACTERISTI...
THEOPHYLLINE TOXICITY, SPECIFIC INGESTION & TREATMENT :
THEOPHYLLINE TOXICITY, SPECIFIC INGESTION & TREATMENT : THEOPHYLLINE : Intro of Drug : Theophylline occurs in tea and cocoa beans in trace amounts. Available dosage forms : Liquid sustained-release tabs, caps & parenteral. Toxicokinetics: · Well absorbed Orally Volume of distribution approx. 0.5L/Kg · Hepatically metabolized · Clearance depends on age, disease states & interacting drugs. Clinical Presentation: · a feeling of loathing · Vomit · Convulsion · Cardiac Dysrhythmias · Chronic toxicity Laboratory Data: A- Theophyll...
HPLC WORKING PRINCIPLE
HPLC WORKING PRINCIPLE HPLC stands for High-Performance Liquid Chromatography, and it is a widely used analytical technique in the field of chemistry. The principle behind HPLC is based on the separation of chemical compounds in a mixture using a stationary phase and a mobile phase. The stationary phase is a material that is packed into a column, typically made of stainless steel, and coated with a thin layer of a specific material. The mobile phase is a liquid that is pumped through the column under high pressure, and it contains a mixture of compounds to be separated. As the mobile phase flows through the column, the individual compounds in the mixture interact differently with the stationary phase, based on their chemical properties such as polarity, size, and charge. This results in differential rates of migration, causing the compounds to separate from each other as they move through the column. As each co...
QUALITY ASSURANCE
QUALITY ASSURANCE Principle : A broad concept called "Q uality Assurance" encompasses all elements that can have an individual or overall impact on a product's quality. The sum of all the measures made to guarantee that pharmaceutical products are of the quality needed for their intended purpose. Quality assurance consequently takes into account GMP as well as other elements, such as product development and design, that fall outside the purview of following guide. The system of quality assurance appropriate to the manufacture of pharma [1] ceutical products should ensure that: · - Taking into consideration GMP's requirements as well as those of other related codes, such as good laboratory practice (GLP) and good clinical practice (GCP). · - Written specifications for production and control operations and the adoption of GMP standards. · - Job descriptio...